Scientific consensus contradicts this claim.

What's still open

What the evidence found 3 findings
Based on 12 sources:
PubMed peer-reviewed View
ResearchGate peer-reviewed View
PMC peer-reviewed View
The Lancet peer-reviewed View
PMC peer-reviewed View
PMC peer-reviewed View
Adelphi University Scholarly Works institutional View
PMC peer-reviewed View
PMC peer-reviewed View
Medtigo news View
PMC Research Article peer-reviewed View
Psychological Medicine peer-reviewed View
Based on 11 sources:
Medscape Reference institutional View
PMC Article on Antipsychotics and Antidepressants for Psychotic Depression peer-reviewed View
Systematic Review and Network Meta-analysis on Pharmacological Treatments for Psychotic Depression peer-reviewed View
British Journal of Psychiatry peer-reviewed View
medRxiv peer-reviewed View
PMC article by Baghai et al. peer-reviewed View
Psychiatric Times institutional View
Science.gov database institutional View
PMC - NIH peer-reviewed View
Psychiatry Advisor news View
Frontiers in Psychiatry peer-reviewed View
Based on 15 sources:
PMC systematic review peer-reviewed View
PMC systematic review peer-reviewed View
ScienceDirect systematic review peer-reviewed View
PMC peer-reviewed View
Nature peer-reviewed View
ScienceDirect peer-reviewed View
PMC Research Article peer-reviewed View
ResearchGate Publication peer-reviewed View
PMC Research Article peer-reviewed View
PMC meta-analysis peer-reviewed View
Science Direct peer-reviewed View
MDPI Genes peer-reviewed View
PubMed peer-reviewed View
Science Direct peer-reviewed View
ResearchGate peer-reviewed View
What research hasn't answered 3 gaps
Medscape Reference institutional View
PMC Article on Antipsychotics and Antidepressants for Psychotic Depression peer-reviewed View
Systematic Review and Network Meta-analysis on Pharmacological Treatments for Psychotic Depression peer-reviewed View
British Journal of Psychiatry peer-reviewed View
medRxiv peer-reviewed View
PMC systematic review peer-reviewed View
PMC systematic review peer-reviewed View
ScienceDirect systematic review peer-reviewed View
PMC peer-reviewed View
Nature peer-reviewed View
Sources 18 findings
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
2018 Cipriani argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
tree-leaf argumentation
argumentation Unknown
argumentation Unknown
argumentation Unknown
Push back on this read

Think the evidence is read wrong? Present your counter-evidence and we'll evaluate it against the 40 sources behind this analysis.

Related questions
Does growth mindset training actually work? Is chess more talent or practice? Is venting anger actually helpful? Are learning styles real?

Heard something that sounds off?

Generated by reaso.ai's editorial pipeline: claim restated, scientific consensus classified via 3-run majority vote, 18 findings enriched with attribution and study type, narrative written in neutral voice. No individual researcher has signed off on this specific analysis — see methodology for how the pipeline works. Built with Claude Sonnet by Anthropic. Updated April 16, 2026. How we do this →

Written by AI. Sources are linked for verification.